DNB Theory question bank 2022 | Cancer and Benign tumours

This is a 2022 update on previously asked questions in the DNB pediatrics theory exam. The questions are arranged topic-wise.

How to use?

  1. Questions are arranged in chronological order, latest first
  2. Each question is followed by a Numbers.
  3. Numbers in bracket are Year followed by session, 1 is June session, 2 is December session eg. (2022/1) is a question from June 2022 question paper
  4. The number after the bracket is Marks allotted for eg. 5+5 is 5 marks for each subquestion.

Principles of Cancer Diagnosis

  1. Diagnostic tumor markers and their role in the management of specific childhood cancers. (2020/01)5

Principles of Cancer Treatment

  1. Metabolic emergencies in pediatric malignancies. (2020/01)5
  2. Tumour lysis syndrome (2019/2)5
  3. Treatment of tumour lysis syndrome (2018/1)5, (2017/2)6
  4. Enumerate the oncological emergencies occurring in leukemia/lymphomas 2(1/2016)
  5. Define tumour lysis syndrome. Describe the pathophysiology of tumour lysis syndrome. How will you prevent occurrence of tumour lysis syndrome? (11/2)2+4+4
  6. Outline the essential components and pathophysiology of tumor lysis syndrome. Describe its management. (2011/1)2+4+4
  7. Define tumour lysis syndrome. Enlist its important constituents. Outline its etiology and describe the management. (2008/1)10

The Leukemias

  1. Role of immunophenotyping in diagnosis of acute leukemia (2018/2)5
  2. Treatment of standard risk acute lymphoblastic leukemia [2018/1/5]
  3. Outline management of ALL (2017/1) 5
  4. Utility of immunophenotyping in the diagnosis of ALL (2017/1) 5
  5. Treatment of CML
  6. Risk stratification of ALL (2016/2)
  7. Management of Acute Myeloid Leukemia 5(Apr 2016)
  8. a) Classification of childhood leukemias
    b) Management of Tumour lysis syndrome (2014/2)5+5
  9. Utility of immunophenotyping in the diagnosis of leukemia in children. Outline the treatment of acute lymphoblastic leukemia. (2009/2)4+6
  10. Prognostic indicators in Acute Leukemia (2007/2)10
  11. Management of a child with acute leukemia (2006/2)10
  12. Discuss management of a child with acute leukemia (2006/1)10
  13. Management of a case of ALL in a 3-year-old (2003/1)25
  14. Treatment and prognosis of ALL (1997/2)15
  15. Management of CNS Leukemia (1996/1)14


  1. Different types of Lymphomas in children and their Histopathological classification (1993/2)15

Brain Tumors in Childhood

  1. Clinical features and diagnosis of posterior fossa tumors (2018/1/5)


  1. Treatment of Neuroblastoma. (2020/01)5
  2. Neuroblastoma- diagnosis and clinical features [2018/2]5

Neoplasms of the Kidney

  1. Clinical presentation and management of Wilms tumour (2019/1) 5

Histiocytosis Syndromes of Childhood

  1. a. How will you classify childhood Histiocytosis? 2
    b. Describe the diagnostic criteria, clinical manifestations and treatment for hemophagocytic lymphohistiocytosis.
  2. a. Classify childhood histiocytosis. 3
    b. Clinical features and management of a case of Langerhan’s cell histiocytosis. (2015/1)3+4
  3. manifestations and treatment for hemophagocytic lymphohistiocytosis. What are the infections associated with it? (2011/2) 2+2+2+2+2
  4. How will you classify childhood Histiocytosis? Describe the diagnostic criteria, clinical
  5. Classify childhood histiocytosis. Describe the clinical manifestations, diagnosis and treatment of Langerhan’s cell histiocytosis. (2010/1)3+3+2+2
  6. Write in brief the clinical manifestations, laboratory findings and management principles of Langerhans Cell Histocytosis. (2009/1)10
dnb question bank

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